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KMID : 0032220090210040402
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Annals of Dermatology
2009 Volume.21 No. 4 p.402 ~ p.405
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Cutaneous Plexiform Schwannomas in a Patient with Neurofibromatosis Type 2
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Ko Joo-Yeon
Kim Ji-Eun
Kim Young-Hoon
Ro Young-Suck
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Abstract
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Plexiform schwannoma is a rare benign neoplasm of the neural sheath characterized by a multinodular plexiform growth pattern. The tumor usually occurs as an isolated finding, although rare cases have been reported in association with neurofibromatosis type 2 (NF2). A 25-year-old man was admitted for foot drop. He had an asymptomatic skin-colored nodule on his neck that had been present for 10 years. His medical history included local excision of a plexiform schwannoma on his left leg in our dermatology clinic 6 years prior. A histopathological examination of the skin-colored nodule also showed the typical microscopic features of a plexiform schwannoma, including the characteristic Antoni type A areas showing frequent nuclear palisading and Verocay bodies. Magnetic resonance imaging revealed a meningioma and a vestibular schwannoma in the cranium and multiple neurofibromas on the spinal cord. Herein we report a rare case of cutaneous plexiform schwannomas in a patient with NF2.
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KEYWORD
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Neurofibromatosis type 2, Plexiform, Schwannoma
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